Activation of complement during hemodialysis.

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چکیده

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[Activation of complement during hemodialysis].

In hemodialysis using 3 types of dialysis membrane materials [regenerated cellulose (RC), cellulose triacetate (CTA), and polysulfone (PS)], activation of the complement, reduction of white blood cells, and variation of vitronectin (VN) were observed. RC membrane caused a significant reduction of white blood cells and elevations of Bb and soluble membrane attack complex (S-MAC), indicating a st...

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The Effect of Methylprednisolone on Complement Activation during Cardiopulmonary Bypass

____________ _ A prospective randomized trial in 80 patients having heart surgery was undertaken to test the hypothesis that steroids (ST) (methylprednisolone, 30 mg/kg) would prevent or reduce complement activation during cardiopulmonary bypass (CPB) with membrane (MEM) or bubble (BUB) oxygenators. Group I patients had MEM and ST; Group II, MEM without ST; Group III, BUB and ST; Group IV, BUB ...

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Complement Activation

The complement system is the most important biochemical cascade in the blood for the recognition, opsonization, and elimination of foreign materials. To date, the leading causes of death in the United States include cancer, cardiovascular and neurodegenerative diseases, and diabetes. New treatments are urgently needed to treat these devastating diseases and nanotechnology potentially provides n...

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Activation of Complement

Activation of the complement system by IgA has been a controversial subject since Ishizaka et al. (1) and South et al. (2) observed that C1 was not fixed by IgA. Lack of complement activation has also been inferred from reports that secretory IgA antibodies were unable to opsonize or promote bacterial killing in the presence of complement (3 6). On the other hand, there is evidence that some co...

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Complement activation during cardiopulmonary bypass by heparin-protamine interaction.

Circulating concentrations of split products of the third complement factor (C3c and C3d) were measured in five patients before, during and after cardiopulmonary bypass. In all patients, C3d concentrations increased significantly in samples obtained after the administration of protamine sulphate. Similarly, circulating C3c was seen only in those samples obtained immediately after protamine admi...

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ژورنال

عنوان ژورنال: Japanese Journal of Clinical Immunology

سال: 1995

ISSN: 0911-4300,1349-7413

DOI: 10.2177/jsci.18.138